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Human UDP-Glucuronosyltransferases: Effects of altered expression in breast and pancreatic cancer cell lines

Increased aerobic glycolysis and de novo lipid biosynthesis are common characteristics of invasive cancers. UDP-glucuronosyltransferases (UGTs) are phase II drug metabolizing enzymes that in normal cells possess the ability to glucuronidate these lipids and speed their excretion; however, de-regulat...

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Bibliografiske detaljer
Udgivet i:Cancer Biol Ther
Main Authors: Dates, Centdrika R, Fahmi, Tariq, Pyrek, Sebastian J, Yao-Borengasser, Aiwei, Borowa-Mazgaj, Barbara, Bratton, Stacie M, Kadlubar, Susan A, Mackenzie, Peter I, Haun, Randy S, Radominska-Pandya, Anna
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622877/
https://ncbi.nlm.nih.gov/pubmed/25996841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384047.2015.1026480
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