Aberrant CpG methylation of the TFAP2A gene constitutes a mechanism for loss of TFAP2A expression in human metastatic melanoma

Metastatic melanoma is a deadly treatment-resistant form of skin cancer whose global incidence is on the rise. During melanocyte transformation and melanoma progression the expression profile of many genes changes. Among these, a gene implicated in several steps of melanocyte development, TFAP2A, is...

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Publicat a:Epigenetics
Autors principals: Hallberg, Andrea R, Vorrink, Sabine U, Hudachek, Danielle R, Cramer-Morales, Kimberly, Milhem, Mohammed M, Cornell, Robert A, Domann, Frederick E
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2015
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622677/
https://ncbi.nlm.nih.gov/pubmed/25625848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15592294.2014.988062
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