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Regulation of SOD2 in Cancer by Histone Modifications and CpG Methylation: Closing the Loop Between Redox Biology and Epigenetics

Significance: Manganese superoxide dismutase (SOD2), encoded by the nuclear gene SOD2, is a critical mitochondrial antioxidant enzyme whose activity has broad implications in health and disease. Thirty years ago, Oberley and Buettner elegantly folded SOD2 into cancer biology with the free radical th...

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Hlavní autoři: Cyr, Anthony R., Hitchler, Michael J., Domann, Frederick E.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3624766/
https://ncbi.nlm.nih.gov/pubmed/22946823
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2012.4850
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