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Redox regulation of the epigenetic landscape in cancer: A role for metabolic reprogramming in remodeling the epigenome

Cancer arises from normal cells that acquire a series of molecular changes; however, the founding events that create the clonogens from which a tumor will arise and progress have been the subject of speculation. Through the efforts of several generations of cancer biologists it has been established...

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Detalhes bibliográficos
Main Authors: Hitchler, Michael J, Domann, Frederick E
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3508253/
https://ncbi.nlm.nih.gov/pubmed/23022407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2012.09.028
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