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Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells

Many breast cancer cells typically exhibit lower expression of manganese superoxide dismutase (MnSOD) compared to the normal cells from which they arise. This decrease can often be attributed to a defect in the transcription of SOD2, the gene encoding MnSOD; however, the mechanism responsible for th...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Hitchler, Michael J., Oberley, Larry W., Domann, Frederick E.
פורמט: Artigo
שפה:Inglês
יצא לאור: 2008
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633123/
https://ncbi.nlm.nih.gov/pubmed/18845242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.09.005
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