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Epigenetic silencing of SOD2 by histone modifications in human breast cancer cells

Many breast cancer cells typically exhibit lower expression of manganese superoxide dismutase (MnSOD) compared to the normal cells from which they arise. This decrease can often be attributed to a defect in the transcription of SOD2, the gene encoding MnSOD; however, the mechanism responsible for th...

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Detalhes bibliográficos
Main Authors: Hitchler, Michael J., Oberley, Larry W., Domann, Frederick E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2633123/
https://ncbi.nlm.nih.gov/pubmed/18845242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2008.09.005
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