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Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase

A new class of hepatitis C virus (HCV)-targeted therapeutics that is safe, broadly effective and can cope with virus mutations is needed. The HCV's NS5B is highly conserved and different from human protein, and thus it is an attractive target for anti-HCV therapeutics development. In this study...

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Dettagli Bibliografici
Pubblicato in:MAbs
Autori principali: Thueng-in, Kanyarat, Thanongsaksrikul, Jeeraphong, Jittavisutthikul, Surasak, Seesuay, Watee, Chulanetra, Monrat, Sakolvaree, Yuwaporn, Srimanote, Potjanee, Chaicumpa, Wanpen
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2014
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622650/
https://ncbi.nlm.nih.gov/pubmed/25517317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29978
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