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Interference of HCV replication by cell penetrable human monoclonal scFv specific to NS5B polymerase

A new class of hepatitis C virus (HCV)-targeted therapeutics that is safe, broadly effective and can cope with virus mutations is needed. The HCV's NS5B is highly conserved and different from human protein, and thus it is an attractive target for anti-HCV therapeutics development. In this study...

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Detalhes bibliográficos
Publicado no:MAbs
Main Authors: Thueng-in, Kanyarat, Thanongsaksrikul, Jeeraphong, Jittavisutthikul, Surasak, Seesuay, Watee, Chulanetra, Monrat, Sakolvaree, Yuwaporn, Srimanote, Potjanee, Chaicumpa, Wanpen
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622650/
https://ncbi.nlm.nih.gov/pubmed/25517317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29978
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