Cell Penetrable Human scFv Specific to Middle Domain of Matrix Protein-1 Protects Mice from Lethal Influenza

A new anti-influenza remedy that can tolerate the virus antigenic variation is needed. Influenza virus matrix protein-1 (M1) is highly conserved and pivotal for the virus replication cycle: virus uncoating, assembly and budding. An agent that blocks the M1 functions should be an effective anti-influ...

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Bibliographic Details
Published in:Viruses
Main Authors: Dong-din-on, Fonthip, Songserm, Thaweesak, Pissawong, Tippawan, Srimanote, Potjanee, Thanongsaksrikul, Jeeraphong, Thueng-in, Kanyarat, Moonjit, Pattra, Lertwatcharasarakul, Preeda, Seesuay, Watee, Chaicumpa, Wanpen
Format: Artigo
Language:Inglês
Published: MDPI 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4306832/
https://ncbi.nlm.nih.gov/pubmed/25594836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7010154
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