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Improving target cell specificity using a novel monovalent bispecific IgG design
Monovalent bispecific IgGs cater to a distinct set of mechanisms of action but are difficult to engineer and manufacture because of complexities associated with correct heavy and light chain pairing. We have created a novel design, “DuetMab,” for efficient production of these molecules. The platform...
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| Wydane w: | MAbs |
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| Główni autorzy: | , , , , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Taylor & Francis
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622537/ https://ncbi.nlm.nih.gov/pubmed/25621507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19420862.2015.1007816 |
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