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Degradation of C-terminal tag sequences on domain antibodies purified from E. coli supernatant

Expression of recombinant proteins often takes advantage of peptide tags expressed in fusion to allow easy detection and purification of the expressed proteins. However, as the fusion peptides most often are flexible appendages at the N- or C-terminal, proteolytic cleavage may result in removal of t...

詳細記述

保存先:
書誌詳細
出版年:MAbs
主要な著者: Lykkemark, Simon, Mandrup, Ole Aalund, Friis, Niels Anton, Kristensen, Peter
フォーマット: Artigo
言語:Inglês
出版事項: Taylor & Francis 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4622476/
https://ncbi.nlm.nih.gov/pubmed/25426869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.36211
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