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Site-specific antibody-drug conjugation through an engineered glycotransferase and a chemically reactive sugar
Conjugation of small molecule drugs to specific sites on the antibody molecule has been increasingly used for the generation of relatively homogenous preparations of antibody-drug conjugates (ADCs) with physicochemical properties similar or identical to those of the naked antibody. Previously a meth...
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| I publikationen: | MAbs |
|---|---|
| Huvudupphovsmän: | , , , , , , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Taylor & Francis
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4622437/ https://ncbi.nlm.nih.gov/pubmed/25517304 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/mabs.29889 |
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