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Conjugates of Small Molecule Drugs with Antibodies and Other Proteins

Conjugates of small molecule drugs with antibodies (ADCs) and with other proteins (protein-drug conjugates, PDC) are used as a new class of targeted therapeutics combining the specificity of monoclonal antibodies (mAbs) and other proteins with potent cytotoxic activity of small molecule drugs for th...

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Detalhes bibliográficos
Publicado no:Biomedicines
Main Authors: Feng, Yang, Zhu, Zhongyu, Chen, Weizao, Prabakaran, Ponraj, Lin, Kedan, Dimitrov, Dimiter S.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5423484/
https://ncbi.nlm.nih.gov/pubmed/28548057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/biomedicines2010001
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