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Applications of Glycosyltransferases in the Site-specific Conjugation of Biomolecules and Development of a Targeted Drug Delivery System and Contrast Agents for MRI

BACKGROUND: The delivery of drugs to the proposed site of action is a challenging task. Tissue and cell-specific guiding molecules are being employed to carry a cargo of therapeutic molecule(s). The cargo molecules need to be conjugated in a site-specific manner to the therapeutic molecule(s) in a w...

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Detalhes bibliográficos
Main Authors: Ramakrishnan, Boopathy, Boeggeman, Elizabeth, Qasba, Pradman K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2291282/
https://ncbi.nlm.nih.gov/pubmed/18248315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/17425247.5.2.149
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