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Site-Specific Linking of Biomolecules via Glycan Residues Using Glycosyltransferases
The structural information on glycosyltransferases has revealed that the sugar-donor specificity of these enzymes can be broadened to include modified sugars with a chemical handle that can be utilized for conjugation chemistry. Substitution of Tyr289 to Leu in the catalytic pocket of bovine β-1,4-g...
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| Main Authors: | , , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
2008
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435414/ https://ncbi.nlm.nih.gov/pubmed/18426242 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bp0704034 |
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