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Site-Specific Linking of Biomolecules via Glycan Residues Using Glycosyltransferases

The structural information on glycosyltransferases has revealed that the sugar-donor specificity of these enzymes can be broadened to include modified sugars with a chemical handle that can be utilized for conjugation chemistry. Substitution of Tyr289 to Leu in the catalytic pocket of bovine β-1,4-g...

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Bibliografske podrobnosti
Main Authors: Qasba, Pradman K., Boeggeman, Elizabeth, Ramakrishnan, Boopathy
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2435414/
https://ncbi.nlm.nih.gov/pubmed/18426242
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bp0704034
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