Učitavanje...
Biased dA/dT somatic hypermutation as regulated by the heavy chain intronic iEµ enhancer and 3′Eα enhancers in human lymphoblastoid B cells
Somatic hypermutation (SHM) in immunoglobulin gene (Ig) variable (V) regions is critical for the maturation of the antibody response. It is dependent on the expression of activation-induced cytidine deaminase (AID) and translesion DNA polymerases in germinal center B cells as well as Ig V transcript...
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| Izdano u: | Mol Immunol |
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| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2006
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4621958/ https://ncbi.nlm.nih.gov/pubmed/16412510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molimm.2005.10.018 |
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