Ataxia-telangiectasia mutated (ATM) silencing promotes neuroblastoma progression through a MYCN independent mechanism

Neuroblastoma, a childhood cancer with highly heterogeneous biology and clinical behavior, is characterized by genomic aberrations including amplification of MYCN. Hemizygous deletion of chromosome 11q is a well-established, independent marker of poor prognosis. While 11q22-q23 is the most frequentl...

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Vydáno v:Oncotarget
Hlavní autoři: Mandriota, Stefano J., Valentijn, Linda J., Lesne, Laurence, Betts, David R., Marino, Denis, Boudal-Khoshbeen, Mary, London, Wendy B., Rougemont, Anne-Laure, Attiyeh, Edward F., Maris, John M., Hogarty, Michael D., Koster, Jan, Molenaar, Jan J., Versteeg, Rogier, Ansari, Marc, Gumy-Pause, Fabienne
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2015
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621910/
https://ncbi.nlm.nih.gov/pubmed/26053094
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