The CEACAM1 tumor suppressor is an ATM and p53-regulated gene required for the induction of cellular senescence by DNA damage

The p53 tumor-suppressor protein has a key role in the induction of cellular senescence, an important barrier to cancer development. However, very little is known about the physiological mediators of cellular senescence induced by p53. CEACAM1 is an immunoglobulin superfamily member whose expression...

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Detalhes bibliográficos
Main Authors: Sappino, A-P, Buser, R, Seguin, Q, Fernet, M, Lesne, L, Gumy-Pause, F, Reith, W, Favaudon, V, Mandriota, S J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3412640/
https://ncbi.nlm.nih.gov/pubmed/23552604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/oncsis.2012.7
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