Ataxia Telangiectasia Mutated (ATM) Inhibition Transforms Human Mammary Gland Epithelial Cells

Carriers of mutations in the cell cycle checkpoint protein kinase ataxia telangiectasia mutated (ATM), which represent 1–2% of the general population, have an increased risk of breast cancer. However, experimental evidence that ATM deficiency contributes to human breast carcinogenesis is lacking. We...

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Autori principali: Mandriota, Stefano J., Buser, Raphaële, Lesne, Laurence, Stouder, Christelle, Favaudon, Vincent, Maechler, Pierre, Béna, Frédérique, Clément, Virginie, Rüegg, Curzio, Montesano, Roberto, Sappino, André-Pascal
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2010
Soggetti:
Molecular Bases of Disease
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857118/
https://ncbi.nlm.nih.gov/pubmed/20177072
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.078360
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