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Characterization of an Engineered Src Kinase to Study Src Signaling and Biology

Pharmacologic inhibitors of protein kinases comprise the vast majority of approved signal transduction inhibitors for cancer treatment. An important facet of their clinical development is the identification of the key substrates critical for their driver role in cancer. One approach for substrate id...

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Библиографические подробности
Опубликовано в: :Methods Mol Biol
Главные авторы: Gentry, Leanna R., Karginov, Andrei V., Hahn, Klaus M., Der, Channing J.
Формат: Artigo
Язык:Inglês
Опубликовано: 2016
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621786/
https://ncbi.nlm.nih.gov/pubmed/26501909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-3073-9_12
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