SPOP mutation leads to genomic instability in prostate cancer

Genomic instability is a fundamental feature of human cancer often resulting from impaired genome maintenance. In prostate cancer, structural genomic rearrangements are a common mechanism driving tumorigenesis. However, somatic alterations predisposing to chromosomal rearrangements in prostate cance...

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Vydáno v:eLife
Hlavní autoři: Boysen, Gunther, Barbieri, Christopher E, Prandi, Davide, Blattner, Mirjam, Chae, Sung-Suk, Dahija, Arun, Nataraj, Srilakshmi, Huang, Dennis, Marotz, Clarisse, Xu, Limei, Huang, Julie, Lecca, Paola, Chhangawala, Sagar, Liu, Deli, Zhou, Pengbo, Sboner, Andrea, de Bono, Johann S, Demichelis, Francesca, Houvras, Yariv, Rubin, Mark A
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2015
Témata:
Cell Biology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621745/
https://ncbi.nlm.nih.gov/pubmed/26374986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.09207
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