Prostate cancer-associated mutations in speckle-type POZ protein (SPOP) regulate steroid receptor coactivator 3 protein turnover

The p160 steroid receptor coactivators (SRCs) SRC-1, SRC-2 [nuclear receptor coactivator (NCOA)2], and SRC-3 [amplified in breast cancer 1 (AIB1)/NCOA3] are key pleiotropic “master regulators” of transcription factor activity necessary for cancer cell proliferation, survival, metabolism, and metasta...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Geng, Chuandong, He, Bin, Xu, Limei, Barbieri, Christopher E., Eedunuri, Vijay Kumar, Chew, Sue Anne, Zimmermann, Martin, Bond, Richard, Shou, John, Li, Chao, Blattner, Mirjam, Lonard, David M., Demichelis, Francesca, Coarfa, Cristian, Rubin, Mark A., Zhou, Pengbo, O’Malley, Bert W., Mitsiades, Nicholas
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2013
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3637757/
https://ncbi.nlm.nih.gov/pubmed/23559371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1304502110
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