SPOP Mutations in Prostate Cancer across Demographically Diverse Patient Cohorts

BACKGROUND: Recurrent mutations in the Speckle-Type POZ Protein (SPOP) gene occur in up to 15% of prostate cancers. However, the frequency and features of cancers with these mutations across different populations is unknown. OBJECTIVE: To investigate SPOP mutations across diverse cohorts and validat...

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Detalhes bibliográficos
Main Authors: Blattner, Mirjam, Lee, Daniel J, O'Reilly, Catherine, Park, Kyung, MacDonald, Theresa Y, Khani, Francesca, Turner, Kevin R, Chiu, Ya-Lin, Wild, Peter J, Dolgalev, Igor, Heguy, Adriana, Sboner, Andrea, Ramazangolu, Sinan, Hieronymus, Haley, Sawyers, Charles, Tewari, Ashutosh K, Moch, Holger, Yoon, Ghil Suk, Known, Yong Chul, Andrén, Ove, Fall, Katja, Demichelis, Francecsa, Mosquera, Juan Miguel, Robinson, Brian D, Barbieri, Christopher E, Rubin, Mark A
Formato: Artigo
Idioma:Inglês
Publicado em: Neoplasia Press Inc. 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3924544/
https://ncbi.nlm.nih.gov/pubmed/24563616
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