Association Between Mutation Clearance After Induction Therapy and Outcomes in Acute Myeloid Leukemia

IMPORTANCE: Tests that predict outcomes for patients with acute myeloid leukemia (AML) are imprecise, especially for those with intermediate risk AML. OBJECTIVES: To determine whether genomic approaches can provide novel prognostic information for adult patients with de novo AML. DESIGN, SETTING, AN...

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Pubblicato in:JAMA
Autori principali: Klco, Jeffery M., Miller, Christopher A., Griffith, Malachi, Petti, Allegra, Spencer, David H., Ketkar-Kulkarni, Shamika, Wartman, Lukas D, Christopher, Matthew, Lamprecht, Tamara L., Helton, Nicole M., Duncavage, Eric J., Payton, Jacqueline E., Baty, Jack, Heath, Sharon E., Griffith, Obi L., Shen, Dong, Hundal, Jasreet, Chang, Gue Su, Fulton, Robert, O'Laughlin, Michelle, Fronick, Catrina, Magrini, Vincent, Demeter, Ryan T., Larson, David E., Kulkarni, Shashikant, Ozenberger, Bradley A., Welch, John S, Walter, Matthew J, Graubert, Timothy A., Westervelt, Peter, Radich, Jerald P., Link, Daniel C., Mardis, Elaine R., DiPersio, John F., Wilson, Richard K., Ley, Timothy J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4621257/
https://ncbi.nlm.nih.gov/pubmed/26305651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.2015.9643
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