A common founding clone with TP53 and PTEN mutations gives rise to a concurrent germ cell tumor and acute megakaryoblastic leukemia

We report the findings from a patient who presented with a concurrent mediastinal germ cell tumor (GCT) and acute myeloid leukemia (AML). Bone marrow pathology was consistent with a diagnosis of acute megakaryoblastic leukemia (AML M7), and biopsy of an anterior mediastinal mass was consistent with...

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Veröffentlicht in:Cold Spring Harb Mol Case Stud
Hauptverfasser: Lu, Charles, Riedell, Peter, Miller, Christopher A., Hagemann, Ian S., Westervelt, Peter, Ozenberger, Bradley A., O'Laughlin, Michelle, Magrini, Vincent, Demeter, Ryan T., Duncavage, Eric J., Griffith, Malachi, Griffith, Obi L., Wartman, Lukas D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2016
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4849848/
https://ncbi.nlm.nih.gov/pubmed/27148581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/mcs.a000687
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