טוען...
FACT disrupts nucleosome structure by binding H2A-H2B with conserved peptide motifs
FACT, a heterodimer of Spt16 and Pob3, is an essential histone chaperone. We show that the H2A-H2B binding activity that is central to FACT function resides in short acidic regions near the C-termini of each subunit. Mutations throughout these regions impact binding and cause correlated phenotypes t...
שמור ב:
| הוצא לאור ב: | Mol Cell |
|---|---|
| Main Authors: | , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
|
| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4620744/ https://ncbi.nlm.nih.gov/pubmed/26455391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.09.008 |
| תגים: |
הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!
|