A carregar...

A Practical, Multi-gram Synthesis of (±)-Herbindole A, (±)-Herbindole B, and (±)-Herbindole C from a Common Intermediate via 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Cross-Coupling Reactions

A practical, multi-gram 10-step synthesis of racemic herbindole A, B, and C from a common intermediate is described. The key step features a remarkably regioselective C-7 metal-halogen exchange and elimination from a Bartoli-generated N-t-butyldimethylsilyl-4,6,7-tribromo-5-methylindole scaffold to...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Tetrahedron Lett
Main Authors: Chandrasoma, Nalin, Pathmanathan, Sivadarshini, Buszek, Keith R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620576/
https://ncbi.nlm.nih.gov/pubmed/26516291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.02.064
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!