Loading...

A Practical, Multi-gram Synthesis of (±)-Herbindole A, (±)-Herbindole B, and (±)-Herbindole C from a Common Intermediate via 6,7-Indole Aryne Cycloaddition and Pd(0)-Catalyzed Cross-Coupling Reactions

A practical, multi-gram 10-step synthesis of racemic herbindole A, B, and C from a common intermediate is described. The key step features a remarkably regioselective C-7 metal-halogen exchange and elimination from a Bartoli-generated N-t-butyldimethylsilyl-4,6,7-tribromo-5-methylindole scaffold to...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Tetrahedron Lett
Main Authors: Chandrasoma, Nalin, Pathmanathan, Sivadarshini, Buszek, Keith R.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4620576/
https://ncbi.nlm.nih.gov/pubmed/26516291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tetlet.2015.02.064
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!