How to Choose In Vitro Systems to Predict In Vivo Drug Clearance: A System Pharmacology Perspective

The use of in vitro metabolism data to predict human clearance has become more significant in the current prediction of large scale drug clearance for all the drugs. The relevant information (in vitro metabolism data and in vivo human clearance values) of thirty-five drugs that satisfied the entry c...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biomed Res Int
Prif Awduron: Wang, Lei, Chiang, ChienWei, Liang, Hong, Wu, Hengyi, Feng, Weixing, Quinney, Sara K., Li, Jin, Li, Lang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Hindawi Publishing Corporation 2015
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619875/
https://ncbi.nlm.nih.gov/pubmed/26539530
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/857327
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