Three‐Component Mixture Model‐Based Adverse Drug Event Signal Detection for the Adverse Event Reporting System

The US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) is an important source for detecting adverse drug event (ADE) signals. In this article, we propose a three‐component mixture model (3CMM) for FAERS signal detection. In 3CMM, a drug‐ADE pair is assumed to have either a...

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Publicat a:CPT Pharmacometrics Syst Pharmacol
Autors principals: Zhang, Pengyue, Li, Meng, Chiang, Chien‐Wei, Wang, Lei, Xiang, Yang, Cheng, Lijun, Feng, Weixing, Schleyer, Titus K., Quinney, Sara K., Wu, Heng‐Yi, Zeng, Donglin, Li, Lang
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2018
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118321/
https://ncbi.nlm.nih.gov/pubmed/30091855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12294
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