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Three‐Component Mixture Model‐Based Adverse Drug Event Signal Detection for the Adverse Event Reporting System

The US Food and Drug Administration (FDA) Adverse Event Reporting System (FAERS) is an important source for detecting adverse drug event (ADE) signals. In this article, we propose a three‐component mixture model (3CMM) for FAERS signal detection. In 3CMM, a drug‐ADE pair is assumed to have either a...

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發表在:CPT Pharmacometrics Syst Pharmacol
Main Authors: Zhang, Pengyue, Li, Meng, Chiang, Chien‐Wei, Wang, Lei, Xiang, Yang, Cheng, Lijun, Feng, Weixing, Schleyer, Titus K., Quinney, Sara K., Wu, Heng‐Yi, Zeng, Donglin, Li, Lang
格式: Artigo
語言:Inglês
出版: John Wiley and Sons Inc. 2018
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6118321/
https://ncbi.nlm.nih.gov/pubmed/30091855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12294
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