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The Cancer Drug Fraction of Metabolism Database

This study aims to create a database for quantifying the fraction of metabolism of cytochrome P450 isozymes for cancer drugs approved by the US Food and Drug Administration. A reproducible data collection protocol was developed to extract essential information, including both substrate‐depletion and...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Hua, Liyan, Chiang, Chien‐Wei, Cong, Wang, Li, Jin, Wang, Xueying, Cheng, Lijun, Feng, Weixing, Quinney, Sara K., Wang, Lei, Li, Lang
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6656935/
https://ncbi.nlm.nih.gov/pubmed/31206254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12417
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