Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage

BACKGROUND: To examine whether metabotropic glutamate (mGlu) receptors have any role in mechanisms that shape neuronal vulnerability to ischemic damage, we used the 4-vessel occlusion (4-VO) model of transient global ischemia in rats. 4-VO in rats causes a selective death of pyramidal neurons in the...

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Vydáno v:Mol Brain
Hlavní autoři: Motolese, Marta, Mastroiacovo, Federica, Cannella, Milena, Bucci, Domenico, Gaglione, Anderson, Riozzi, Barbara, Lütjens, Robert, Poli, Sonia M., Celanire, Sylvain, Bruno, Valeria, Battaglia, Giuseppe, Nicoletti, Ferdinando
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
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Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619332/
https://ncbi.nlm.nih.gov/pubmed/26496940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0158-2
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