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Targeting type-2 metabotropic glutamate receptors to protect vulnerable hippocampal neurons against ischemic damage
BACKGROUND: To examine whether metabotropic glutamate (mGlu) receptors have any role in mechanisms that shape neuronal vulnerability to ischemic damage, we used the 4-vessel occlusion (4-VO) model of transient global ischemia in rats. 4-VO in rats causes a selective death of pyramidal neurons in the...
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Publicado no: | Mol Brain |
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Main Authors: | , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619332/ https://ncbi.nlm.nih.gov/pubmed/26496940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-015-0158-2 |
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