Genetic deletion of mGlu2 metabotropic glutamate receptors improves the short-term outcome of cerebral transient focal ischemia

We have recently shown that pharmacological blockade of mGlu2 metabotropic glutamate receptors protects vulnerable neurons in the 4-vessel occlusion model of transient global ischemia, whereas receptor activation amplifies neuronal death. This raised the possibility that endogenous activation of mGl...

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Dades bibliogràfiques
Publicat a:Mol Brain
Autors principals: Mastroiacovo, Federica, Moyanova, Slavianka, Cannella, Milena, Gaglione, Anderson, Verhaeghe, Remy, Bozza, Giovanna, Madonna, Michele, Motolese, Marta, Traficante, Anna, Riozzi, Barbara, Bruno, Valeria, Battaglia, Giuseppe, Lodge, David, Nicoletti, Ferdinando
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2017
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5562974/
https://ncbi.nlm.nih.gov/pubmed/28821279
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-017-0319-6
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