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Loss of CDC4/FBXW7 in Gastric Carinoma
Background: CDC4/FBXW7, encoding a ubiquitin ligase, maps to 4q32 and has been implicated as a tumor suppressor gene and therapeutic target in many tumor types. Mutations in colonic adenomas, and the frequent losses on 4q described in gastric cancer prompt speculation about the role of CDC4/FBXW7 in...
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Publicado no: | Cell Oncol |
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Main Authors: | , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
IOS Press
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4619292/ https://ncbi.nlm.nih.gov/pubmed/20448329 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/CLO-2010-523 |
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