Prognostic Significance of NOTCH1 and FBXW7 Mutations in Pediatric T-ALL

The NOTCH signaling pathway plays important role in the development of multicellular organisms, as it regulates cell proliferation, survival, and differentiation. In adults, it is essential for the T- or B-lymphocyte lineage commitment. NOTCH1 and FBXW7 mutations both lead the activation of the NOTC...

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Main Authors: Erbilgin, Yucel, Sayitoglu, Muge, Hatirnaz, Ozden, Dogru, Omer, Akcay, Arzu, Tuysuz, Gulen, Celkan, Tiraje, Aydogan, Gonul, Salcioglu, Zafer, Timur, Cetin, Yuksel-Soycan, Lebriz, Ure, Umit, Anak, Sema, Agaoglu, Leyla, Devecioglu, Omer, Yildiz, Inci, Ozbek, Ugur
Format: Artigo
Sprog:Inglês
Udgivet: IOS Press 2010
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Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3833232/
https://ncbi.nlm.nih.gov/pubmed/20683149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/DMA-2010-0715
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