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A Possible Role for WNT5A Hypermethylation in Pediatric Acute Lymphoblastic Leukemia
OBJECTIVE: WNT5A is one of the most studied noncanonical WNT ligands and is shown to be deregulated in different tumor types. Our aim was to clarify whether hypermethylation might be the cause of low WNT5A mRNA levels and whether we could restore this downregulation by reversing the event. MATERIALS...
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| Publicado no: | Turk J Haematol |
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| Main Authors: | , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Galenos Publishing
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4451480/ https://ncbi.nlm.nih.gov/pubmed/26316480 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2013.0296 |
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