A Possible Role for WNT5A Hypermethylation in Pediatric Acute Lymphoblastic Leukemia

OBJECTIVE: WNT5A is one of the most studied noncanonical WNT ligands and is shown to be deregulated in different tumor types. Our aim was to clarify whether hypermethylation might be the cause of low WNT5A mRNA levels and whether we could restore this downregulation by reversing the event. MATERIALS...

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Bibliografiska uppgifter
I publikationen:Turk J Haematol
Huvudupphovsmän: Hatırnaz Ng, Özden, Fırtına, Sinem, Can, İsmail, Karakaş, Zeynep, Ağaoğlu, Leyla, Doğru, Ömer, Celkan, Tiraje, Akçay, Arzu, Yıldırmak, Yıldız, Timur, Çetin, Özbek, Uğur, Sayitoğlu, Müge
Materialtyp: Artigo
Språk:Inglês
Publicerad: Galenos Publishing 2015
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4451480/
https://ncbi.nlm.nih.gov/pubmed/26316480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4274/tjh.2013.0296
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