Mechanical Loading Synergistically Increases Trabecular Bone Volume and Improves Mechanical Properties in the Mouse when BMP Signaling Is Specifically Ablated in Osteoblasts

Bone homeostasis is affected by several factors, particularly mechanical loading and growth factor signaling pathways. There is overwhelming evidence to validate the importance of these signaling pathways, however, whether these signals work synergistically or independently to contribute to proper b...

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Publicat a:PLoS One
Autors principals: Iura, Ayaka, McNerny, Erin Gatenby, Zhang, Yanshuai, Kamiya, Nobuhiro, Tantillo, Margaret, Lynch, Michelle, Kohn, David H., Mishina, Yuji
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619208/
https://ncbi.nlm.nih.gov/pubmed/26489086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0141345
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