Loss of BMP signaling through BMPR1A in osteoblasts leads to greater collagen cross-link maturation and material-level mechanical properties in mouse femoral trabecular compartments

Bone morphogenetic protein (BMP) signaling pathways play critical roles in skeletal development and new bone formation. Our previous study, however, showed a negative impact of BMP signaling on bone mass because of the osteoblast-specific loss of a BMP receptor (i.e. BMPR1A) showing increased trabec...

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Foilsithe in:Bone
Main Authors: Zhang, Yanshuai, McNerny, Erin Gatenby, Terajima, Masahiko, Raghavan, Mekhala, Romanowicz, Genevieve, Zhang, Zhanpeng, Zhang, Honghao, Kamiya, Nobuhiro, Tantillo, Margaret, Zhu, Peizhi, Scott, Gregory J., Ray, Manas K., Lynch, Michelle, Ma, Peter X., Morris, Michael D., Yamauchi, Mitsuo, Kohn, David H., Mishina, Yuji
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4899267/
https://ncbi.nlm.nih.gov/pubmed/27113526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2016.04.022
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