Bone morphogenetic protein signaling through ACVR1 and BMPR1A negatively regulates bone mass along with alterations in bone composition

Bone quantity and bone quality are important factors in determining the properties and the mechanical functions of bone. This study examined the effects of disrupting bone morphogenetic protein (BMP) signaling through BMP receptors on bone quantity and bone quality. More specifically, we disrupted t...

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Detalhes bibliográficos
Publicado no:J Struct Biol
Main Authors: Shi, Ce, Mandair, Gurjit S, Zhang, Honghao, Vanrenterghem, Gloria G., Ridella, Ryan, Takahashi, Akira, Zhang, Yanshuai, Kohn, David H., Morris, Michael D, Mishina, Yuji, Sun, Hongchen
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5820174/
https://ncbi.nlm.nih.gov/pubmed/29175363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jsb.2017.11.010
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