Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass

Bone morphogenetic proteins (BMPs) are known as ectopic bone inducers. The FDA approved BMPs (BMP2 and BMP7) for clinical use. However, direct effects of BMPs on endogenous bone metabolism are not yet well known. We conditionally disrupted BMP receptor type IA (BMPRIA) in osteoblasts during weanling...

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מידע ביבליוגרפי
Main Authors: Kamiya, Nobuhiro, Ye, Ling, Kobayashi, Tatsuya, Lucas, Donald J, Mochida, Yoshiyuki, Yamauchi, Mitsuo, Kronenberg, Henry M, Feng, Jian Q, Mishina, Yuji
פורמט: Artigo
שפה:Inglês
יצא לאור: Amer Soc Bone & Mineral Res. 2008
נושאים:
Original Articles
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686924/
https://ncbi.nlm.nih.gov/pubmed/18684091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080809
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