Disruption of BMP Signaling in Osteoblasts Through Type IA Receptor (BMPRIA) Increases Bone Mass

Bone morphogenetic proteins (BMPs) are known as ectopic bone inducers. The FDA approved BMPs (BMP2 and BMP7) for clinical use. However, direct effects of BMPs on endogenous bone metabolism are not yet well known. We conditionally disrupted BMP receptor type IA (BMPRIA) in osteoblasts during weanling...

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Hlavní autoři: Kamiya, Nobuhiro, Ye, Ling, Kobayashi, Tatsuya, Lucas, Donald J, Mochida, Yoshiyuki, Yamauchi, Mitsuo, Kronenberg, Henry M, Feng, Jian Q, Mishina, Yuji
Médium: Artigo
Jazyk:Inglês
Vydáno: Amer Soc Bone & Mineral Res. 2008
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2686924/
https://ncbi.nlm.nih.gov/pubmed/18684091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1359/JBMR.080809
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