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BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway
Bone morphogenetic proteins (BMPs) are known to induce ectopic bone. However, it is largely unknown how BMP signaling in osteoblasts directly regulates endogenous bone. This study investigated the mechanism by which BMP signaling through the type IA receptor (BMPR1A) regulates endogenous bone mass u...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2694443/ https://ncbi.nlm.nih.gov/pubmed/18927151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025825 |
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