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BMP signaling negatively regulates bone mass through sclerostin by inhibiting the canonical Wnt pathway

Bone morphogenetic proteins (BMPs) are known to induce ectopic bone. However, it is largely unknown how BMP signaling in osteoblasts directly regulates endogenous bone. This study investigated the mechanism by which BMP signaling through the type IA receptor (BMPR1A) regulates endogenous bone mass u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kamiya, Nobuhiro, Ye, Ling, Kobayashi, Tatsuya, Mochida, Yoshiyuki, Yamauchi, Mitsuo, Kronenberg, Henry M., Feng, Jian Q., Mishina, Yuji
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2008
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2694443/
https://ncbi.nlm.nih.gov/pubmed/18927151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.025825
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