Flavivirus sfRNA suppresses antiviral RNA interference in cultured cells and mosquitoes and directly interacts with the RNAi machinery

Productive arbovirus infections require mechanisms to suppress or circumvent the cellular RNA interference (RNAi) pathway, a major antiviral response in mosquitoes. In this study, we demonstrate that two flaviviruses, Dengue virus and Kunjin virus, significantly repress siRNA-mediated RNAi in infect...

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Detaylı Bibliyografya
Yayımlandı:Virology
Asıl Yazarlar: Moon, Stephanie L., Dodd, Benjamin J.T., Brackney, Doug E., Wilusz, Carol J., Ebel, Gregory D., Wilusz, Jeffrey
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619171/
https://ncbi.nlm.nih.gov/pubmed/26331679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.009
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