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Flavivirus sfRNA suppresses antiviral RNA interference in cultured cells and mosquitoes and directly interacts with the RNAi machinery

Productive arbovirus infections require mechanisms to suppress or circumvent the cellular RNA interference (RNAi) pathway, a major antiviral response in mosquitoes. In this study, we demonstrate that two flaviviruses, Dengue virus and Kunjin virus, significantly repress siRNA-mediated RNAi in infect...

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Dettagli Bibliografici
Pubblicato in:Virology
Autori principali: Moon, Stephanie L., Dodd, Benjamin J.T., Brackney, Doug E., Wilusz, Carol J., Ebel, Gregory D., Wilusz, Jeffrey
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619171/
https://ncbi.nlm.nih.gov/pubmed/26331679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2015.08.009
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