Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes

Flaviviruses, such as Zika virus, yellow fever virus, dengue virus, and West Nile virus (WNV), are a serious concern for human health. Flaviviruses produce an abundant noncoding subgenomic flavivirus RNA (sfRNA) in infected cells. sfRNA results from stalling of the host 5′-3′ exoribonuclease XRN1/Pa...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Göertz, G. P., Fros, J. J., Miesen, P., Vogels, C. B. F., van der Bent, M. L., Geertsema, C., Koenraadt, C. J. M., van Rij, R. P., van Oers, M. M., Pijlman, G. P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105652/
https://ncbi.nlm.nih.gov/pubmed/27581979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00930-16
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