Noncoding Subgenomic Flavivirus RNA Is Processed by the Mosquito RNA Interference Machinery and Determines West Nile Virus Transmission by Culex pipiens Mosquitoes

Flaviviruses, such as Zika virus, yellow fever virus, dengue virus, and West Nile virus (WNV), are a serious concern for human health. Flaviviruses produce an abundant noncoding subgenomic flavivirus RNA (sfRNA) in infected cells. sfRNA results from stalling of the host 5′-3′ exoribonuclease XRN1/Pa...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Göertz, G. P., Fros, J. J., Miesen, P., Vogels, C. B. F., van der Bent, M. L., Geertsema, C., Koenraadt, C. J. M., van Rij, R. P., van Oers, M. M., Pijlman, G. P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2016
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5105652/
https://ncbi.nlm.nih.gov/pubmed/27581979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00930-16
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