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The structural basis of pathogenic subgenomic flavivirus RNA (sfRNA) production
Flaviviruses are emerging human pathogens and worldwide health threats. During infection, a pathogenic, subgenomic flaviviral RNAs (sfRNAs) are produced by resisting degradation by the 5’→3’ host cell exonuclease Xrn1 through an unknown RNA structure-based mechanism. Here, we present the crystal str...
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| Hauptverfasser: | , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4163914/ https://ncbi.nlm.nih.gov/pubmed/24744377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1250897 |
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