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RNA structures that resist degradation by Xrn1 produce a pathogenic Dengue virus RNA

Dengue virus is a growing global health threat. Dengue and other flaviviruses commandeer the host cell’s RNA degradation machinery to generate the small flaviviral RNA (sfRNA), a noncoding RNA that induces cytopathicity and pathogenesis. Host cell exonuclease Xrn1 likely loads on the 5′ end of viral...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chapman, Erich G, Moon, Stephanie L, Wilusz, Jeffrey, Kieft, Jeffrey S
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: eLife Sciences Publications, Ltd 2014
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3968743/
https://ncbi.nlm.nih.gov/pubmed/24692447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.01892
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