Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology

BACKGROUND: Alterations in methylation patterns, miRNA expression, and stem cell protein expression occur in germ cell tumors (GCTs). Our goal is to integrate molecular data across platforms to identify molecular signatures in the three main histologic subtypes of Type I and Type II GCTs (yolk sac t...

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Dades bibliogràfiques
Publicat a:BMC Cancer
Autors principals: Poynter, Jenny N., Bestrashniy, Jessica R. B. M., Silverstein, Kevin A. T., Hooten, Anthony J., Lees, Christopher, Ross, Julie A., Tolar, Jakub
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619074/
https://ncbi.nlm.nih.gov/pubmed/26497383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1796-6
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