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Cross platform analysis of methylation, miRNA and stem cell gene expression data in germ cell tumors highlights characteristic differences by tumor histology

BACKGROUND: Alterations in methylation patterns, miRNA expression, and stem cell protein expression occur in germ cell tumors (GCTs). Our goal is to integrate molecular data across platforms to identify molecular signatures in the three main histologic subtypes of Type I and Type II GCTs (yolk sac t...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Poynter, Jenny N., Bestrashniy, Jessica R. B. M., Silverstein, Kevin A. T., Hooten, Anthony J., Lees, Christopher, Ross, Julie A., Tolar, Jakub
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4619074/
https://ncbi.nlm.nih.gov/pubmed/26497383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1796-6
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